Table 4.

Systolic blood pressure after injury.

Hours after CCI	0 (CCI)	6 h	24 h	48 h	72 h	96 h	120 h
Age 2 months Vehicle	133 ± 14*	107 ± 19	109 ± 20	129 ± 21	116 ± 15	110 ± 20	125 ± 16
Age 2 months Candesartan	130 ± 18*	99 ± 15	125 ± 13	132 ± 8	130 ± 14	111 ± 15	111 ± 19
Age 21 months Vehicle	108 ± 22*	87 ± 26	109 ± 26	108 ± 18	111 ± 24	102 ± 23	101 ± 16
Age 21 months Candesartan	96 ± 15*	91 ± 16	118 ± 20	111 ± 27	98 ± 17	95 ± 5	109 ± 10

Systolic blood pressure [mmHg] during five posttraumatic days was within physiologic range and not affected by candesartan treatment. At time point 0 that represents intraoperative measurement immediately after CCI induction under general anesthesia (in italic characters) systolic blood pressure was higher in young than in old mice (*p < 0.05). Following measurements were performed in awake animals.