Table 1. Comparison of the clinipathological characteristics of basaloid squamous cell carcinoma (BSC), squamous cell carcinoma of the lung (SCC), large cell carcinoma of the lung (LCC) and lung adenocarcinoma (LAC).
| Characteristics | BSC | SCC | p value | LCC | p value | LAC | p value |
|---|---|---|---|---|---|---|---|
| Race, n (%) | 0.351 | 0.039 | 0.049 | ||||
| White | 358 (84.2) | 75,272 (83.6) | 5,682 (81.2) | 128,685 (80.1) | |||
| Black | 43 (10.1) | 10,617 (11.8) | 999 (14.3) | 18,644 (11.6) | |||
| Other | 24 (5.7) | 4,117 (4.6) | 316 (4.5) | 13,309 (8.3) | |||
| Age, median [IQR] | 70.15 (59.87–80.43) | 70.41 (60.66–80.16) | 0.139 | 67.92 (56.87–78.97) | 0.303 | 68.37 (57.27–79.47) | 0.376 |
| Sex, n (%) | 0.503 | 0.443 | <0.001 | ||||
| Male | 257 (60.5) | 55,849 (62.1) | 4,099 (58.6) | 78,527 (48.9) | |||
| Female | 168 (39.5) | 34,157 (37.9) | 2,898 (41.4) | 82,111 (51.1) | |||
| Grade, n (%) | <0.001 | <0.001 | <0.001 | ||||
| Well differetiated | 2 (0.5) | 1,974 (2.2) | 15 (0.2) | 11,955 (7.4) | |||
| Moderately differetiated | 46 (10.8) | 26,606 (29.6) | 80 (1.1) | 36,005 (22.4) | |||
| Poorly differetiated | 274 (64.5) | 32,307 (35.9) | 2,115 (30.2) | 43,291 (27.0) | |||
| Undifferetiated | 13 (3.0) | 648 (0.7) | 2,299 (32.9) | 968 (0.6) | |||
| Unknown | 90 (21.2) | 28,471 (31.6) | 2,488 (35.6) | 68,419 (42.6) | |||
| Total stage, n (%) | <0.001 | <0.001 | <0.001 | ||||
| I | 179 (42.1) | 27,683 (30.8) | 1,460 (20.9) | 41,408 (25.8) | |||
| II | 63 (14.8) | 10,946 (12.2) | 534 (7.6) | 10,560 (6.6) | |||
| III | 101 (23.8) | 26,297 (29.2) | 1,858 (26.6) | 32,528 (20.2) | |||
| IV | 82 (19.3) | 25,080 (27.8) | 3,145 (44.9) | 76,142 (47.4) | |||
| T stage, n (%) | <0.001 | <0.001 | 0.001 | ||||
| T1 | 133 (31.3) | 9,151 (10.2) | 1,292 (10.2) | 43,558 (27.1) | |||
| T2 | 139 (32.7) | 66,275 (73.6) | 2,346 (73.6) | 47,776 (29.8) | |||
| T3 | 68 (16.0) | 3,596 (4.0) | 880 (4.0) | 22,072 (13.7) | |||
| T4 | 85 (20.0) | 10,984 (12.2) | 2,479 (12.2) | 47,232 (29.4) | |||
| N stage, n (%) | <0.001 | <0.001 | <0.001 | ||||
| N0 | 269 (63.3) | 9,151 (10.2) | 2,847 (40.7) | 72,104 (44.9) | |||
| N1 | 50 (11.8) | 66,275 (73.6) | 663 (9.5) | 14,110 (8.8) | |||
| N2 | 84 (19.8) | 3,596 (4.0) | 2,628 (37.5) | 54,487 (33.9) | |||
| N3 | 22 (5.1) | 10,984 (12.2) | 859 (12.3) | 19,937 (12.4) | |||
| M stage, n (%) | <0.001 | <0.001 | <0.001 | ||||
| M0 | 343 (80.7) | 58,972 (65.5) | 3,854 (55.1) | 84,496 (52.6) | |||
| M1 | 82 (19.3) | 31,034 (34.5) | 3,143 (44.9) | 76,142 (47.4) | |||
| Surgery, n (%) | <0.001 | <0.001 | <0.001 | ||||
| Not performed | 144 (33.9) | 60,336 (67.0) | 5,041 (72.0) | 112,857 (70.3) | |||
| Lobectomy | 199 (46.8) | 20,978 (23.3) | 1,377 (19.7) | 35,329 (22.0) | |||
| Sublobar resection | 62 (14.6) | 6,153 (6.8) | 438 (6.3) | 10,982 (6.8) | |||
| Pneumonectomy | 20 (4.7) | 2,539 (2.8) | 141 (2.0) | 1,470 (0.9) | |||
| Radiotherapy, n (%) | <0.001 | <0.001 | <0.001 | ||||
| No | 104 (24.5) | 4 (0.0) | 3,980 (56.9) | 98,823 (61.5) | |||
| Yes | 321 (75.5) | 90,002 (100.0) | 3,017 (43.1) | 61,815 (38.5) | |||
| Chemotherapy, n (%) | <0.001 | <0.001 | <0.001 | ||||
| No | 134 (31.5) | 53,403 (59.3) | 3,944 (56.4) | 88,220 (54.9) | |||
| Yes | 291 (68.5) | 36,603 (40.7) | 3,053 (43.6) | 72,418 (45.1) |
Notes.
P value for chi-square test.
- BSC
- Basaloid squamous cell carcinoma
- SCC
- squamous cell carcinoma
- LCC
- large cell carcinoma of the lung
- LAC
- lung adenocarcinoma
- IQR
- interquartile range