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. 2019 Apr 20;149(5):804–815. doi: 10.1093/jn/nxy319

FIGURE 1.

FIGURE 1

Multivariable-adjusted weight change (kilograms per 4 y) in women for each 1 SD increment in the change in dietary insulinemic (EDIH) and inflammatory (EDIP) potential, stratified by selected characteristics. Values are mean (95% CI) weight change in each 4-y interval. Analyses were adjusted for age, questionnaire cycle, baseline total energy intake, changes in total energy intake, baseline dietary insulinemic or inflammatory potential at the beginning of each 4-y period, baseline BMI, baseline physical activity, changes in physical activity, baseline hours of sleep per day, hours of sitting and watching TV per week (baseline only in NHS), 4-y change in alcohol consumption, 4-y change in smoking status, baseline parity, menopausal status, and postmenopausal hormone use. When stratifying by BMI, physical activity, age, and baseline dietary insulinemic or inflammatory potential, we adjusted for the continuous variable within strata of the potential effect modifier, e.g., adjusting for continuous BMI among normal weight women. The sample sizes in the strata of the potential effect modifiers (listed in order of the 4-y intervals: 1986–90, 1990–94, 1994–98, 1998–2002, 2002–06, 2006–10) were as follows: normal weight (BMI <25 kg/m2): 32,072, 22,343, 14,714, 9804, 5571, 3136; overweight or obese (BMI ≥25): 21,993, 18,195, 16,181, 12,615, 7853, 4460; high physical activity (at or above median, 20.8 MET-h/wk): 27,774, 20,289, 15,895, 11,979, 7791, 4599; low physical activity (below median) 26,291, 21,761, 15,694, 10,934, 6990, 3570; age ≥55 y: 20,927, 20,521, 19,147, 18,412, 14,781, 8169; age <55 y: 33,138, 21,529, 12,442, 4501, no woman was <55 y after 2002; ever smokers: 29,355, 22,631, 16,859, 12,065, 7621, 4143; never smokers: 24,610, 19,280, 14,601, 10,774, 7096, 4005; baseline EDIH score below median score: 27,028, 20,744, 15,400, 11,081, 7140, 4088; baseline EDIH score above or equal to median score: 27,037, 21,306, 16,189, 11,832, 7641, 4081; baseline EDIP score below median score: 27,060, 21,343, 16,155, 11,923, 7902, 4549; baseline EDIP score above or equal to median score: 27,005, 20,707, 15,434, 10,990, 6879, 3602; premenopausal women: 24,686, 15,388, 7706, 2502, 251, 202; postmenopausal and postmenopausal hormone use never: 14,192, 10,625, 7425, 4532, 2746, 1455; postmenopausal and postmenopausal hormone use ever: 13,887, 14,806, 15,764, 15,363, 11,349, 6112. EDIH, empirical dietary index for hyperinsulinemia score; EDIP, empirical dietary inflammatory pattern score; MET-h/wk, metabolic equivalent hours per week.