FIGURE 2.

Tibrovirus glycoproteins mediate virion entry into a broad range of human cell types. Same experiment as in Figure 1B using rVSIVs expressing diverse tibrovirus G glycoproteins (MOI = 3). The percentage of eGFP-expressing NCI-60 human cell panel cell lines was measured by high-content imaging at 24 h post-exposure. All experiments were performed in triplicates; error bars show standard deviations. BHV, Beatrice Hill virus; BASV, Bas-Congo virus; BAV, Bivens Arm virus; CNS, central nervous system, CPV; Coastal Plains virus; EKV-1, Ekpoma virus 1; EKV-2, Ekpoma virus 2; eGFP, enhanced green fluorescent protein; MOI, multiplicity of infection; NCI, National Cancer Institute; SWBV, Sweetwater Branch virus; TIBV, Tibrogargan virus; rVSIV, recombinant vesicular stomatitis Indiana virus. NCI-60 cell lines are listed by their abbreviations and grouped by organ/cancer type.