Table 1.
Demographics of 92 patients
| Characteristic | Total | Initial episode cases | Relapse cases | p valuea |
|---|---|---|---|---|
| Male, no. (%) | 45 (49) | 25 | 20 | 0.9818 |
| Female, no. (%) | 47 (51) | 26 | 21 | |
| Age, y | ||||
| Range | 11–81 | 11–80 | 14–81 | |
| Mean (SD) | 39 (19) | 39 (19) | 40 (18) | 0.5876 |
| Median (IQR) | 36 (23–54) | 35 (22–56) | 36 (26–52) | |
| Extent of ulcerative colitis,20 no. (%) | 0.9267 | |||
| Proctitis | 15 (16) | 9 | 6 | |
| Left-sided colitis | 22 (24) | 12 | 10 | |
| Extensive colitis | 55 (60) | 30 | 25 | |
| Severity14,20 | 0.0346 | |||
| Mild | 31 (34) | 18 | 13 | |
| Moderate | 48 (52) | 30 | 18 | |
| Severe | 13 (14) | 3 | 10 | |
| Disease duration, mo | ||||
| Range | 1–296 | 1–24 | 1–296 | |
| Mean (SD) | 35 (63) | 3 (4) | 75 (78) | < 0.0001 |
| Median (IQR) | 4 (1–35) | 1 (1–4) | 46 (8–127) | |
| Case referral status, no. (%) | 0.5575 | |||
| Referred | 53 (58) | 28 | 25 | |
| Nonreferred | 39 (42) | 23 | 16 | |
| Smoking status, no. (%) | 0.8190 | |||
| Current smoker | 17 (18) | 9 | 8 | |
| Nonsmoker | 75 (82) | 42 | 33 | |
| Medication during hospitalization, no. (%) | 0.0033 | |||
| None | 11 (12) | 6 | 5 | |
| A: Local (suppository, enema) | 9 (10) | 7 | 2 | |
| B: 5-aminosalicylic acids, oral | 27 (29) | 21 | 6 | |
| C: A and B | 15 (16) | 8 | 7 | |
| Immunomodulator | 30 (33) | 9 | 21 | |
| Prednisolone alone or with any combination of A, B, C, and tacrolimus | 22 | 8 | 14 | |
| Prednisolone and azathioprine and any combination of A, B, C, and CAP | 6 | 1 | 5 | |
| Azathioprine and B or C | 2 | 0 | 2 | |
| Corticosteroid dependent | 5 (5) | 1 | 4 | 0.0950 |
| Previous proctocolectomy | 0 (0) | 0 | 0 | |
| Hospitalization, d | ||||
| Range | 7–125 | 13–125 | 7–121 | |
| Mean (SD) | 37 (27) | 34 (25) | 42 (29) | 0.1142 |
| Median (IQR) | 29 (22–45) | 25 (20–39) | 32 (23–50) | |
| Follow-up period after discharge | ||||
| Mean (SD) | 5 y 11 mo (4 y 3 mo) | 5 y 2 mo (3 y 9 mo) | 6 y 10 mo (4 y 7mo) | 0.0935 |
| Median (IQR) | 5 y 1 mo (2 y 2 mo–9 y 3 mo) | 4 y 1 mo (2 y 1 mo–8 y 1 mo) | 6 y 4 mo (2 y 8 mo–11 y 3 mo) | |
a
Comparison between initial attack cases and relapse cases (χ2 test).
CAP = cytapheresis; IQR = interquartile range; SD = standard deviation.