Table 1.
Summary of variants validated by genome-editing technologies
| ID | Target genes | Traits | Class* | Score* |
|---|---|---|---|---|
| rs737092 | RBM38, RAE1 | Red blood cell | C4 | 0.9536 |
| rs1175550 | SMIM1, LRRC47, CEP104 | Red blood cell | C4 | 0.9509 |
| rs1546723 | CD164, FOXO3, FIG4 | Red blood cell | C4 | 0.9517 |
| rs1421085 | IRX3, IRX5 | Obesity | C4 | 0.9976 |
| rs339331 | RFX6 | Prostate cancer | C1 | 0.9820 |
| rs56069439 | ANKLE1 | Breast cancer | C5 | 0.9702 |
| rs1800734 | DCLK3 | Colorectal cancer | C5 | 0.9512 |
| rs2595104 | PITX2c | Atrial fibrillation | C5 | 0.9711 |
| rs200996365 | CCNE1 | Bladder cancer | C5 | 0.9856 |
*
The class labels and scores are calculated with DVAR-cluster and DVAR-score.