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. Author manuscript; available in PMC: 2019 Jul 2.
Published in final edited form as: Mol Pharm. 2018 Jun 4;15(7):2721–2731. doi: 10.1021/acs.molpharmaceut.8b00237

Figure 4. Effect of free, monomeric 58C-scFv and multivalent 58C-scFv on cellular migration.

Figure 4.

(A) Schematic illustrating the effect of 58C-scFv and liposomal multivalent display of 58C-scFv on cellular migration. (B) TEM image of liposomes surface-decorated with 58C-scFv (high degree of valency), scale bar: 200 nm. Transwell migration assay performed with (C) RAW 264.7 murine macrophages (D) and MDA-MB-231 breast cancer cells. Experiments were performed in triplicate at 88.9 nM. Data are represented as mean ± sd, *p<0.05, **p<0.01, ***p<0.001 with one-way ANOVA followed by Dunnett’s post-test.