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. Author manuscript; available in PMC: 2020 Mar 19.
Published in final edited form as: J Am Coll Cardiol. 2019 Mar 19;73(10):1173–1184. doi: 10.1016/j.jacc.2018.12.053

Figure 5. PDE3A1 mRNA abundance analyzed by RT-PCR in non-failing and failing LVs, by −2214 INS/DEL genotype.

Figure 5.

PDE3A1 mRNA abundance analyzed by RT-PCR in non-failing and failing LVs with and without PDE3 inhibitor treatment, by INS/DEL genotype reveals increased expression in DEL homozygous or DEL carriers failing LVs with previous PDE inhibitor (PDEi) treatment. Values are normalized to 18S rRNA and then to Non-failing Ins/Ins as 100%, represented as 1.0 on the y axis. ANOVA/Newman-Keuls test significance is shown in the Figure (* in comparison to untreated). N.S. – not significant.