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. Author manuscript; available in PMC: 2020 Mar 19.
Published in final edited form as: J Am Coll Cardiol. 2019 Mar 19;73(10):1173–1184. doi: 10.1016/j.jacc.2018.12.053

Figure 6. Microsomal PDE3 enzyme activity in non-failing and failing human LVs (LVs).

Figure 6.

PDE3 activity by genotype in non-failing and failing hearts separated by presence or absence of PDE3 inhibitor treatment, showing increased activity in PDE inhibitor treated failing LVs in DEL homozygotes or DEL carriers. ANOVA/Newman-Keuls test significance is shown in the Figure (* in comparison to untreated). N.S. – not significant.