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Cell-type-specific induction of viperin expression by type I and II IFNs. (A) Viperin is induced in macrophages by IFN-γ. Extracts of untreated and IFN-γ-treated primary human macrophages were subjected to SDS/PAGE and viperin was detected by immunoblotting with a specific rabbit antiserum. (B) Induction of viperin in macrophages by type I and II IFNs. (C) Viperin expression is stimulated preferentially by type I IFNs in a variety of other cell types.
