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. 2019 May 3;14(5):e0216416. doi: 10.1371/journal.pone.0216416

Table 2. Correlations between logarithmic serum ucOC and OC concentrations and each parameter in univariate models.

ucOC (ng/ml) OC (ng/ml) Log ucOC (ng/ml) Log OC (ng/ml)
r P r P r P r P
Age (years) -0.157 0.184 -0.178 0.132 -0.186 0.114 -0.193 0.102
Duration of diabetes (years) -0.174 0.140 -0.176 0.137 -0.138 0.243 -0.143 0.229
BMI (kg/m2) -0.184 0.120 -0.176 0.137 -0.204 0.084 -0.185 0.117
TDD (units) -0.032 0.788 -0.030 0.798 0.012 0.918 -0.009 0.942
TDD/kg (units/kg) 0.061 0.607 0.057 0.635 0.089 0.456 0.061 0.611
Basal (units) -0.040 0.738 -0.030 0.803 0.011 0.923 -0.002 0.984
Basal/kg (units/kg) 0.040 0.737 0.053 0.658 0.065 0.584 0.061 0.608
Bolus (units) -0.021 0.860 -0.024 0.838 0.010 0.933 -0.010 0.931
Bolus/kg (units/kg) 0.049 0.680 0.036 0.762 0.067 0.575 0.036 0.764
HbA1c (%) -0.086 0.473 -0.116 0.334 -0.057 0.635 -0.127 0.288
eGFR (ml/min/1.73 m2) -0.203 0.086 -0.231 0.050 -0.103 0.387 -0.168 0.155
Albuminuria (mg/gCr) 0.074 0.535 0.102 0.389 0.028 0.816 0.085 0.475
%Body fat (%) -0.261 0.028* -0.278 0.019* -0.319 0.007* -0.321 0.006*
Adiponectin (μg/ml) -0.078 0.511 -0.060 0.617 -0.140 0.237 -0.070 0.554
Free-testosterone (pg/ml)
(in males)
0.081 0.719 0.104 0.644 0.074 0.743 0.079 0.726
SMI (kg/m2) -0.060 0.622 -0.043 0.719 -0.061 0.613 -0.017 0.885
Grip strength (kg) 0.017 0.887 0.030 0.800 0.146 0.222 0.124 0.298
Knee extension strength (kg) 0.014 0.908 0.055 0.642 0.103 0.386 0.116 0.330
Gait speed (m/s) -0.055 0.649 0.005 0.969 0.009 0.943 0.084 0.483

* Statistically significant (P < 0.05).

ucOC, undercarboxylated osteocalcin; OC, osteocalcin; BMI, body mass index; MDI, multiple daily injection of insulin; CSII, continuous subcutaneous insulin infusion; TDD, total daily dose of insulin; TDD/kg, body weight-adjusted total daily dose of insulin; Basal, basal dose of insulin; Basal/kg, body weight-adjusted basal dose of insulin; Bolus, bolus dose of insulin; Bolus/kg, body weight-adjusted bolus dose of insulin; HbA1c, glycated hemoglobin; eGFR, estimated glomerular filtration rate; SMI, skeletal muscle mass index.