Figure 2.

Comparison of methods when simulating phenotypes with additive effects and using chromosome six only (scenario N°2). Thinner lines represent results in scenario N°1. Mean AUC over 100 simulations for PLR and the maximum values of C+T for three different $r^2$ thresholds (0.05, 0.2, and 0.8) as a function of the number and location of causal SNPs. Upper (lower) panels present results for effects following a Gaussian (Laplace) distribution and left (right) panels present results for a heritability of 0.5 (0.8). Error bars representing $\pm 2\text{SD}$ of ${10}^5$ nonparametric bootstrap of the mean AUC. The blue dotted line represents the maximum achievable AUC.