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. 2019 Apr 23;10(30):2911–2920. doi: 10.18632/oncotarget.26885
(C)
Copies of EGFR/mL 4416 (Stdev±14.4)
Copies exon 19 deletion Δ746-750 /mL 0 2 2.9 5.4 5.2 7.1 8.6 12.8 27.9 50 Total
Fractional abundance (%)/mL 0 0.05 0.07 0.12 0.12 0.16 0.19 0.29 0.63 1.12
Detected 0 5 4 5 5 5 5 5 5 5 45
Not detected 5 0 1 0 0 0 0 0 0 0 5
Hit Fraction* 0 1.0 0.75 1.0 1.0 1.0 1.0 1.0 1.0 1.0

Analytical performance was assessed by spiking mutations into healthy pooled plasma. Spike-ins were done in 2 mL plasma aliquots, but copies are depicted as copies/mL.