(C) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Copies of EGFR/mL | 4416 (Stdev±14.4) | ||||||||||
Copies exon 19 deletion Δ746-750 /mL | 0 | 2 | 2.9 | 5.4 | 5.2 | 7.1 | 8.6 | 12.8 | 27.9 | 50 | Total |
Fractional abundance (%)/mL | 0 | 0.05 | 0.07 | 0.12 | 0.12 | 0.16 | 0.19 | 0.29 | 0.63 | 1.12 | |
Detected | 0 | 5 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 45 |
Not detected | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 |
Hit Fraction* | 0 | 1.0 | 0.75 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
Analytical performance was assessed by spiking mutations into healthy pooled plasma. Spike-ins were done in 2 mL plasma aliquots, but copies are depicted as copies/mL.