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. Author manuscript; available in PMC: 2020 Jun 15.
Published in final edited form as: Stat Med. 2019 Mar 18;38(13):2428–2446. doi: 10.1002/sim.8120

Figure 4.

Figure 4.

Survival (left) and AIDS-free survival (right) under each monitoring and treatment strategy, CNICS and HIV-CAUSAL Collaboration 2000–2015. The curves are standardized by the baseline covariates: sex, CD4 cell count (≤200, 201–350, 351–500, ≥501 cells/μl), years since HIV diagnosis (<1, 1 to 4, ≥5 years, unknown), race (white, black, other or unknown), geographic origin (N. America/W. Europe, Sub-Saharan Africa, other, unknown), acquisition group (heterosexual, homosexual or bisexual, injection drug use, other or unknown), calendar year (restricted cubic splines with 3 knots at 2001, 2007 and 2011), age (restricted cubic splines with 3 knots at 25, 39 and 60), cohort, and months from treatment initiation to virologic suppression (2–4, 5–8, ≥9).