. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Transfusion. 2019 Feb 20;59(5):1880–1881. doi: 10.1111/trf.15217

Table 2.

Genetic variations detected in ICAM4 gene in 57 Ethiopian individuals from Gambela

Location	Nucleotide change^*	dbSNP reference no.	Observations in present study (n=57)					Caucasian VAF²	African American VAF²	Global VAF^†
Location	Nucleotide change^*	dbSNP reference no.	Homozygote reference	Heterozygote variant	Homozygote variant	VAF	HWE (p)	Caucasian VAF²	African American VAF²	Global VAF^†
Promoter	c.−286C>T	rs3093030	54	3	0	0.042	0.838	0.361	0.143	0.320
Intron 1	c.394+7G>A	rs5030384	55	2	0	0.017	0.896	0.000	0.000	0.004

Nucleotide substitutions are shown relative to the reference sequence (NG_007728.1). Nucleotide positions are defined using the first nucleotide of the coding sequence (CDs) of NM_001544.5 isoform 1 as nucleotide position 1

^†

Global VAF from 1000Genome, TOPMed (nhlbiwgs.org) and gnomAD (http://gnomad.broadinstitute.org/) databases

VAF - variant allele frequency, HWE – Hardy-Weinberg equilibrium