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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Dig Dis Sci. 2018 Dec 17;64(5):1171–1181. doi: 10.1007/s10620-018-5417-5

Figure 2: Concentration-dependent relaxation by IVA in colonic segments.

Figure 2:

Colonic segments were equilibrated in an organ bath. The segments were allowed to equilibrate at 1 g tension for 1 h before the addition of acetylcholine (10 μM). During the sustained phase of ACh-induced contraction, segments were treated with different concentrations of IVA (10–50 mM). IVA inhibited ACh-induced contraction in a concentration-dependent fashion. Results are expressed as percent of inhibition of ACh-induced contraction by IVA. Values are means±SEM of 35–50 experiments.