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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Dig Dis Sci. 2018 Dec 17;64(5):1171–1181. doi: 10.1007/s10620-018-5417-5

Figure 4: Concentration-dependent relaxation by IVA in isolated colonic muscle cells.

Figure 4:

Relaxation of muscle cells was measured as decrease in maximal cell contraction induced by ACh. Muscle cells were treated with ACh (1 μM) in the absence or presence of pre-treatment with different concentrations (1–100 μM) of IVA. IVA inhibited (i.e. caused relaxation) ACh-induced contraction in a concentration-dependent fashion. Relaxation was expressed percent inhibition of contraction. Values are means±SD.