Table 1.
Publication | Addiction | Concurrent Treatment | n | Target | Anode | Cathode | Current density mA/cm |
No. Sessions | Objective Outcome Measure | Primary Outcome Measure | Mean % change |
---|---|---|---|---|---|---|---|---|---|---|---|
Boggio et al. 2009 | nicotine | NR | 27 | DLPFC | F3, 35 cms2 | F4, 100 cms2 | 0.06 | 5 | no | Cue-elicited craving | NI |
At last session: Active: 2.6 | |||||||||||
Sham = 4.18 | |||||||||||
SD | |||||||||||
Fecteau et al. 2014 | nicotine | NR | 12 | DLPFC | F4, 35 cms2 | F3, 35cms2 | 0.06 | 5 | Expired CO2, ultimatum game and risk task | Expired CO2 | NI |
NS | |||||||||||
da Silva et al. 2013 | alcohol | Yes | 13 | DLPFC | F3, 35 cms2 | R supradeltoid, 35 cms2 | 0.06 | 5 | ERPs to alcohol and neutral cue exposure with LORETA | Relapse | Active: 67% RE |
Sham: 14% RE | |||||||||||
NS | |||||||||||
Klauss et al. 2014 | alcohol | Yes | 35 | DLPFC | F4, 35 cms2 | F3, 35cms2 | 0.06 | 10 (2 per day) | FAB | Relapse | At last session: NI |
NS | |||||||||||
Relapse at 6 months | |||||||||||
Active: 50% RE | |||||||||||
Sham: 88% RE | |||||||||||
SD | |||||||||||
Conti and Nakamura-Palacios 2014 | crack cocaine | NR | 13 | DLPFC | F4, 35 cms2 | F3, 35cms2 | 0.06 | 5 | ERPs to cue exposure with LORETA | N2 component in ACC during crack pics | NI |
SD | |||||||||||
Batista et al. 2015 | crack cocaine | NR | 17 pts., 19 controls | DLPFC | F4, 35 cms2 | F3, 35cms2 | 0.06 | 5 | no (urine samples showed no use during study - in rehab) | Craving | NI |
SD | |||||||||||
Ljubisavljevic et al. 2016 | food | NR | 27 | F4, 35 cms2 | L supraorbit, 35 cms2 | 0.06 | no | Craving* | Active: 14% | ||
FCQ-T | Sham: 5% | ||||||||||
SD |
NR, not reported; NI, pre and post mean data not included; SD, significantly different; NS, no significant difference found; DLPFC, dorsolateral prefrontal cortex; LORETA, low-resolution brain electromagnetic tomography; FAB, Frontal Assessment Battery; FCQ-T, Food Craving Questionnaire - Trait: *, primary outcome measure not specified; RE, relapse