Table 1.
Patient Demographics (n = 29) | Decliners (n = 11) | Stables (n = 18) | Total (n = 29) |
---|---|---|---|
Median Age at Study Enrolment (IQR) | 63 (39–70) | 57 (50–68) | 60 (48–69) |
Median FEV1 at enrolment (% predicted) (IQR) | 71 (45–93) | 53 (39–67) | 55% (40.5–74) |
Respiratory Comorbidities | |||
Sinusitis | 5 (45%) | 10 (56%) | 15 (52%) |
Asthma | 1 (9%) | 3 (17%) | 4 (14%) |
Chronic Obstructive Pulmonary Disease (COPD) | 0 | 2 (11%) | 2 (7%) |
Treatments Recorded During Sample Collection | |||
Inhaled corticosteroids | 7 (64%) | 14 (78%) | 21 (72%) |
Long-acting beta-agonists (LABA) | 6 (55%) | 14 (78%) | 20 (69%) |
Long-acting muscarinic antagonist (LAMA) | 1 (9%) | 8 (44%) | 9 (31%) |
Short-acting beta-agonists (SABA) | 6 (55%) | 12 (67%) | 18 (62%) |
Ipratropium bromide | 3 (27%) | 7 (39%) | 10 (34%) |
Saline | 2 (18%) | 4 (22%) | 6 (21%) |
Proton-pump inhibitors | 1 (9%) | 2 (11%) | 3 (10%) |
H2-receptor antagonists | 1 (9%) | 1 (6%) | 2 (7%) |
Cultured Pathogens | |||
Pseudomonas aeruginosa | 6 (55%) | 10 (56%) | 16 (55%) |
Haemophilus influenzae | 4 (36%) | 4 (22%) | 8 (28%) |
Staphylococcus aureus | 3 (27%) | 5 (28%) | 8 (28%) |
Moraxella catarrhalis | 2 (18%) | 1 (6%) | 3 (10%) |
Streptococcus pneumoniae | 1 (9%) | 3 (17%) | 4 (14%) |
Inter-quartile Range (IQR) and percent are indicated by the parenthesis.