Table 2.
Screening of phenotypes in wild type worms after treatment with O6-BG at the indicated concentrations.
| Control | O6-BG (0.05 mM) | O6-BG (2 mM) | |
|---|---|---|---|
| Parental | 18 | 18 | 18 |
| Laid eggs | 4046 | 3250 | 3145 |
| Brood size | 225 | 181 | 175 |
| Dead embryos (%) | 0.5 | 2.9 | 15 |
| Developmental defects (%) | 0 | 0.8 | 7 |
The percentage of embryonic lethality was calculated as the ratio of the total unviable eggs on the total laid eggs. The percentage of developmental defects was calculated as the ratio of aberrant larval phenotypes on hatched eggs.