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. 2019 May 3;9:6876. doi: 10.1038/s41598-019-43345-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Schematic illustration of Morris water maze (MWM). The pool was divided into four quadrants (N, north; S, south; E, east, W, west). A platform with 8 cm diameter was placed one cm below the water level in the middle of one of the quadrants as the hidden goal platform. The rat swimming from the start point to the goal was tracked by a video camera connected to a video tracking system. Image of rat from Mind the Graph (https://mindthegraph.com/) under a CC BY SA 4.0 licence (https://creativecommons.org/licenses/by-sa/4.0/).