Table 2.

Comparison between FM-only males with complete and incomplete FMR1 mRNA silencing on intellectual functioning (corrected) scores and autism features

	FM-only with incomplete FMR1 mRNA silencing			FM-only with complete FMR1 mRNA silencing			p
	n	M	SD	n	M	SD
Intellectual Functioninga
cVIQ	33	37.0	26.9	21	41.5	20.4	0.196
cPIQ	33	36.8	20.6	21	44.4	19.5	0.980
cFSIQ	33	22.9	24.3	21	28.4	23.2	0.497
Autism features (whole sample)b
ADOS CSS	30	7.23	1.74	20	5.90	2.29	0.041
SA CSS	30	7.07	2.00	20	5.95	2.56	0.035
RRB CSS	30	7.73	1.57	20	6.70	2.30	0.202
Autism features (< 19 years)b
ADOS CSS	24	7.29	1.85	16	5.31	2.09	0.011*
SA CSS	24	7.08	2.19	16	5.50	2.61	0.029*
RRB CSS	24	7.83	1.66	16	6.50	2.42	0.171
Autism features (< 13 years)b
ADOS CSS	19	7.16	1.92	13	5.31	2.18	0.050
SA CSS	19	7.11	2.21	13	5.15	2.58	0.047
RRB CSS	19	7.68	1.77	13	6.77	2.45	0.647

^aSemi-parametric regression adjusted for country, ADOS CSS and age

^bRobust regression adjusted for country and cFSIQ; *p value remained < 0.05 after adjustment for multiple testing

Italic values indicate significance prior to adjustment for multiple testing