Table 4.

Relationship between intellectual functioning (corrected) scores, and autism features, with FMR1 mRNA levels in FM-only males with incomplete FMR1 mRNA silencing and PM/FM mosaic males

	FM-only with incomplete FMR1 mRNA silencing			PM/FM mosaic
	n	β ± se	p	n	β ± se	p
Intellectual functioning
cVIQ	32	14.7 ± 38.7	0.705	12	13.6 ± 4.52	0.003*
cPIQ	32	13.5 ± 25.3	0.594	13	14.8 ± 3.77	< 0.001*
cFSIQ	32	6.75 ± 27.6	0.807	12	9.62 ± 4.28	0.025*
Autism features
ADOS CSS	29	− 0.78 ± 0.77	0.310	12	− 0.85 ± 0.87	0.331
SA CSS	29	− 0.60 ± 0.98	0.538	12	− 0.79 ± 1.04	0.448
RRB CSS	29	− 0.92 ± 0.96	0.338	12	− 1.16 ± 0.65	0.074

Robust regression was used to conduct analysis, without adjustment for any covariate. *p value remained < 0.05 after adjustment for multiple testing

Italic values indicate significance prior to adjustment for multiple testing