Table 1.

Characteristics and variables to be extracted from the included articles

Characteristics	Variables
Study characteristics	Reference; study type; country; context
Population	Participants number; amount of groups; age in years; eligibility criteria; sample selection method; treatment performed; type of AML
Exposures	SNP; DNA localization; related gene; altered nitrogen bases
Outcomes	Toxicity (degree and type); disease-free and global survival; response to treatment
Results	Description of the data; confidence intervals and p values of the study, survival and treatment response in randomized clinical trials; assessment of outcomes in cohort and case-control studies