Table 1.
Outcomes and measurements
| Outcomes | Measurements | |
|---|---|---|
| 1. Primary | TWA MAP drop under 65 mmHg threshold | Intraoperative record from EV1000 monitor, Edwards Lifesciences |
| 2. Secondary | TWA MAP drop under 60 mmHg threshold | Intraoperative record from EV1000 monitor, Edwards Lifesciences |
| TWA MAP drop under 55 mmHg threshold | Intraoperative record from EV1000 monitor, Edwards Lifesciences | |
| 3. Exploratory | Composite of death, stroke, or MINS | From Cleveland Clinic Perioperative Health Documentation System PHDS and troponin first three postoperative mornings while in hospital from EHR |
| Acute kidney injury | AKIN, creatinine | |
| Quality of recovery (QoR-15) | POD 3, patient interview | |
| Post-operative morbidity survey (POMS) | POD 3, EHR | |
| Transfusion requirements (ml) | From PHDS | |
| Amounts of intraoperative crystalloid and colloid (ml) | From PHDS | |
| Amount of vasoactive: phenylephrine, ephedrine, nor-epinephrine, epinephrine, dobutamine (mg) | From PHDS | |
| Advanced hemodynamic variables | From EV100 | |
| Hospital length of stay | From PHDS | |
| Hospital readmission within 30 days | From EHR |
AKIN Acute Kidney Injury Network, EHR electronic health record, MAP mean arterial pressure, MINS myocardial injury in non-cardiac surgery, PHDS Perioperative health documentation system, PHDS POD post-operative day, TWA time-weighted average