The protein levels of ROCK1 and ROCK2 were inhibited by ROCK short-interfering RNAs (siRNAs) in prostate cancer cells, PC-3 and DU145. (A, C, E) The protein levels of ROCK1 were inhibited in siROCK1 (RNAi1-1, RNAi1-2, and RNAi1-3) transfected cells. (B, D, F) The protein levels of ROCK2 were inhibited in siROCK2 (RNAi2-1, RNAi2-2, and RNAi2-3) transfected cells. ** P<0.01 vs. normal control (NC).