Table 2.
Condition | Value | Source |
Phagosome lumen volume, L | 8.5 × 10−16 | * |
T. cruzi volume, L | 3.6 × 10−15 | * |
T. cruzi superficial area, cm2 | 1.2 × 10−7 | * |
O2 consumed per phagosome, mol/s | 1 × 10−17 | * |
Phagosome pH | 5.3 | * |
Membrane O2•− permeability, cm/s | 2.1 × 10−6 | † |
Membrane HO2• permeability, cm/s | 9 × 10−4 | ‡ |
O2•− diffusion rate constant, s−1 | 0.3 | * |
HO2• diffusion rate constant, s−1 | 130 | * |
Phagosome O2•− steady-state concentration, μM | 28 | * |
Phagosome HO2• steady-state concentration, μM | 8 | * |
O2•− diffusion rate, μM/s (mol/s) | 2 (7.1 × 10−21) | * |
HO2• diffusion rate, μM/s (mol/s) | 240 (8.6 × 10−19) | * |
Fe-SODB concentration, μM | 28 | * |
Rate constant for Fe-SODB and O2•−, M−1⋅s−1 | 7.6 × 108 | § |
Obtained as detailed in Materials and Methods.
Takahashi and Asada (44).
Korshunov and Imlay (63).
Martinez et al. (18).