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. 2019 Apr 15;116(18):8985–8994. doi: 10.1073/pnas.1822013116

Fig. 6.

Fig. 6.

Serum levels of mtDNA are significantly increased during EAE. Sera were collected from naïve C57BL/6 mice (n = 24) or C57BL/6 mice with chronic EAE at different weeks after disease induction (2 wk, n = 12; 3 wk, n = 13; 6 wk, n = 38). Data represent serum mtDNA concentration (ng/mL) of individual mice tested in duplicate. Bars indicate mean values. *P < 0.05; ****P < 0.0001, Kruskal–Wallis test with Dunn’s multiple comparisons test.