Table 1.

Example search strategies

Keyword	MEDLINE	Embase
Population=adults	No search strategy	No search strategy
Intervention/Test=aortic calcification	exp Vascular Calcification/or exp Calcinosis/or exp Vascular Diseases/or arterial calcification.mp or exp Arteriosclerosis/or exp Arterial Occlusive Diseases/or exp Aortic Diseases/or aortic.mp or vascular calcifications.mp. or exp Vascular Calcification/or calcified atherosclerosis.mp or calcification.mp or calcified atherosclerotic plaque.mp or arterial calcium.mp or aortic calcification.mp or aorta calcification.mp and aort$.mp and calc$.mp	vascular calcification.mp. or exp blood vessel calcification/or artery calcification.mp. or exp artery calcification/or exp coronary artery disease/or exp arteriosclerosis/or calcified atherosclerosis.mp or arterial calcium.mp or calcified atherosclerotic plaque.mp or calcification.mp or aortic calcification.mp or aorta calcification.mp or vascular calcifications.mp or arteriosclerosis.mp or extracoronary.mp and aort$.mp and calc$.mp
Methodology=observational	No search strategy	No search strategy
Comparator=None	No search strategy	No search strategy
Outcome =	bone mineral density.mp or exp Bone Density/or Fracture.mp or Fractures.mp	bone mineral density.mp or exp bone density/or fracture.mp or fractures.mp or exp fracture/
Additional specific filters	Human	Human

The reference lists of recent literature reviews and guidelines will be hand searched for possibly relevant studies.