Table 2.
Characteristics of study subjects according to the presence of diastolic dysfunction
| Variables | No diastolic dysfunction | Diastolic dysfunction | P value |
| (n=182) | (n=470) | ||
| Age (year) | 52.6±8.8 | 60.3±8.1 | <0.001 |
| Male sex, n (%) | 93 (51.1) | 268 (57.0) | 0.172 |
| BMI (kg/m2) | 23.4±3 | 25±3.2 | <0.001 |
| SBP (mm Hg) | 116.2±12.6 | 122.6±13.7 | <0.001 |
| DBP (mm Hg) | 71.4±8.6 | 75.3±8.8 | <0.001 |
| Hb (g/L) | 144±15.2 | 148.9±14.5 | <0.001 |
| FBS (mmol/L) | 5.6±1 | 6.1±1.6 | <0.001 |
| TC (mmol/L) | 5.4±1 | 5.4±1.1 | 0.958 |
| TG (mmol/L) | 1.2±0.8 | 1.5±1 | <0.001 |
| HDL-C (mmol/L) | 1.6±0.4 | 1.5±0.4 | <0.001 |
| LDL-C (mmol/L) | 3.2±1 | 3.2±1 | 0.996 |
| Creatinine (μmol/L) | 76.3±15.5 | 79±15.2 | 0.040 |
| eGFR (mL/min/1.73 m2) | 88.9±15.7 | 84.3±15 | 0.001 |
| NT-proBNP (pg/mL) | 35.9±63.5 | 32.3±32.9 | 0.476 |
| LVEF (%) | 65.2±6.9 | 66.1±6.5 | 0.131 |
| LVMI (g/m2) | 69.5±14.2 | 75.9±15.3 | <0.001 |
| LAD (mL/m2) | 33.9±5.1 | 35±4.7 | 0.007 |
| E/e’ | 9.4±2.1 | 12±3.6 | <0.001 |
| e’ (cm/s) | 8.4±3.6 | 5.3±1 | <0.001 |
Continuous variables are expressed as mean±SD values and were compared using Student’s t-test. Categorical variables are expressed as N (%) values and were analysed using the χ2 test.
BMI, body mass index; DBP, diastolic blood pressure; e’, mean e’ septal and lateral wall velocity; E/e’, mitral early flow velocity/early diastolic tissue velocity; eGFR, estimated glomerular filtration rate; FBS, fasting blood sugar; Hb, haemoglobin; HDL-C, high-density lipoprotein cholesterol; LAD, left atrial dimension; LDL-C, low-density liporotein cholesterol; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; NT-proBNP, N-terminal pro-B-type natriuretic peptide; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride.