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. Author manuscript; available in PMC: 2019 May 4.
Published in final edited form as: Nat Rev Gastroenterol Hepatol. 2018 Nov;15(11):683–698. doi: 10.1038/s41575-018-0053-2

Fig. 1 |. Mechanisms underlying the association between energy balance and obesity-related gastrointestinal cancers.

Fig. 1 |

Line thickness corresponds to the current evidence for the strength of the effect or association. Black lines represent positive or enhancing effects, and red lines represent negative or inhibiting effects. IGF, insulin-like growth factor.