Table 1.
Baseline patient characteristics of the obstructive uropathy cohort
Cases (n = 27) | Controls (n = 41) | p | |
---|---|---|---|
Age at baseline (years) | 10.0 (9−13) | 10.0 (9−13) | 0.950 |
Age at outcome (years) | 15.9 (12.7, 16.9) | 15.8 (12.7, 16.6) | 0.821 |
Male sex | 23 (85.2) | 33 (80.5) | 0.751 |
Nonwhite race | 7 (25.9) | 18 (43.9) | 0.133 |
GFR (mL/min per 1.73 m2) | 36.9 (28.6, 42.2) | 53.5 (44.5, 64.6) | < 0.0001* |
Urine protein/Cr (mg/mg) | 0.40 (0.23, 0.84) | 0.22 (0.11, 0.47) | 0.010* |
Urine microalbumin/Cr** (mg/mg) | 0.58 (0.27, 1.68) | 0.03 (0.01, 0.14) | < 0.0001* |
Serum CO2 (mmol/L) | 20 (18, 20) | 22 (20, 25) | 0.002* |
Serum phosphate (mg/dL) | 4.6 (4.3, 5.1) | 4.5 (3.9, 4.8) | 0.125 |
Serum albumin (g/dL) | 4.3 (4.2, 4.4) | 4.4 (4.3, 4.5) | 0.270 |
Serum hemoglobin (g/dL) | 12.4 (11.4, 13.3) | 13.2 (12.3, 14.3) | 0.020* |
Follow-up duration (years) | 4.9 (3.4, 5.9) | 6.8 (5.2, 7.7) | < 0.001* |
Controls matched to cases by age at study entry and time on study. Data reported as median (interquartile range) for continuous variables and n (%) for categorical variables
GFR glomerular filtration rate, Cr creatinine, n number
Clinical significance (p < 0.05)
Urine microalbumin/Cr estimated at 3–5 years before matched case