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. 2019 Apr 30;14:3069–3086. doi: 10.2147/IJN.S179837

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© 2019 Patel et al.

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Schematic diagram (A) of the experimental setup for sum frequency generation (SFG) spectroscopy analysis of lipid bilayer-peptide interactions; SFG O-H/N-H stretching signals collected from 22A peptide associated with egg sphingomyelin (eSM) at 20°C (B), 37°C (C), and 50°C (D); SFG amide range stretching signals collected from 22A peptide associated with eSM at 37°C (E) and 50°C (F); ppp refers to polarization combination of p-polarized SFG, p-polarized visible, p-polarized IR and ssp refers to s-polarized SFG, s-polarized visible, p-polarized IR.