Table 3.
Adverse events experienced by the patients (N=55)
| Adverse events | Grade | Total | ||||
|---|---|---|---|---|---|---|
| 1 or 2 | 3 or 4 | |||||
| No. | % | No. | % | No. | % | |
| Gastrointestinal | ||||||
| Loss of appetite | 14 | 25.4 | 0 | 0 | 14 | 25.4 |
| Nausea | 18 | 32.7 | 0 | 0 | 18 | 32.7 |
| Vomiting | 14 | 25.4 | 1 | 1.8 | 15 | 27.2 |
| Hepatic | ||||||
| Increase of aminotransferase | 14 | 25.4 | 0 | 0 | 14 | 25.4 |
| Increase of bilirubin | 6 | 10.9 | 0 | 0 | 6 | 10.9 |
| Hematologic | ||||||
| Leucopenia | 13 | 23.6 | 1 | 1.8 | 14 | 25.4 |
| Thrombocytopenia | 14 | 25.4 | 1 | 1.8 | 15 | 27.2 |
| Decrease of hemoglobin | 12 | 21.8 | 0 | 0 | 12 | 21.8 |
| Others | ||||||
| Increase of LDH | 2 | 3.6 | 0 | 0 | 2 | 3.6 |
| Increase of creatinase | 1 | 1.8 | 0 | 0 | 1 | 1.8 |
| Fever | 20 | 36.4 | 0 | 0 | 20 | 36.4 |
| Fatigue | 5 | 9.1 | 0 | 0 | 5 | 9.1 |
| Hypertension | 2 | 3.6 | 0 | 0 | 2 | 3.6 |
| Trichomadesis | 4 | 7.3 | 0 | 0 | 4 | 7.3 |
Abbreviations: No, number; LDH, lactate dehydrogenase.