Figure 3.

Crude In-Hospital Mortality and Predicted Risk of In-Hospital Death After the Time of Sepsis Protocol Initiation

Crude in-hospital mortality (bars) and the predicted risks of in-hospital death with 95%CIs (orange line with error bars). Predicted risks derive from model adjusted for age category, payer, protocol initiation site, diagnosis of septic shock, site of infection, platelet count <150 000μL at protocol initiation, chronic renal failure or renal disease, diabetes, acute respiratory failure requiring mechanical ventilation, serum lactate, and transfer status across 4 hours after protocol initiation for the completion of the 1-hour bundle of sepsis care. As an interpretive example, for a typical pediatric patient with sepsis with average age and level of acuity in New York State, the completion of the 1-hour sepsis bundle within 1 hour was associated with an 8% risk of in-hospital death. In contrast, the same patient who completes the bundle at 4 hours will have a 13% predicted risk of in-hospital death.