Skip to main content
. Author manuscript; available in PMC: 2019 May 4.
Published in final edited form as: Expert Opin Drug Saf. 2016 Jun 16;15(9):1175–1183. doi: 10.1080/14740338.2016.1194823

Table 2.

Reporting trends for seizure reports after 2014-2015 inactivated influenza vaccines (IIV) compared to 2013-2104 through 2004-2005 influenza seasons. Note the higher proportion of seizure reports among children aged 6-23 months during 2010-2011 (24.83%) and 2011-2012 (30.8%) influenza seasons compared to other seasons. 2010 – 2011 is the season during which a febrile seizure signal first appeared in VAERS and it continued for one more season.

Reporting trends of SEIZURE Reports with Onset Interval 0-1 Day
Following 2014-15 Inactivated Seasonal Influenza Vaccines (IIV)a
Compared to 2013-14 Inactivated Seasonal Influenza Vaccines (IIV) through 2004-05 (IIV) (by season)
By age-group and all ages, initial domestic reports only, VAERS reports as of 03/27/2015b
 
6-23 mos 2-4 yrs All ages
Season Total
Reports
Seizure
N (%)
Total Seizure
N (%)
Total
Reports
Seizure
N (%)
2014-15 IIV 174 27 (15.52%) 151 4 (2.65%) 6000 75 (1.25%)
2013-14 IIV 175 30 (17.14%) 162 13 (8.02%) 5960 93 (1.56%)
2012-13 IIV 155 16 (10.32%) 156 11 (7.05%) 5513 69 (1.25%)
2011-12 IIV 276 85 (30.80%) 147 12 (8.16%) 5088 140 (2.75%)
2010-11 IIV 298 74 (24.83%) 223 16 (7.17%) 5930 140 (2.36%)
2009-10 IIV 253 36 (14.23%) 216 13 (6.02%) 4342 94 (2.16%)
2008-09 IIV 183 30 (16.39%) 148 6 (4.05%) 2960 63 (2.13%)
2007-08 IIV 224 50 (22.32%) 152 12 (7.89%) 2336 78 (3.34%)
2006-07 IIV 169 31 (18.34%) 134 2 (1.49%) 1836 46 (2.51%)
2005-06 IIV 159 23 (14.47%) 112 5 (4.46%) 1847 47 (2.54%)
2004-05 IIV 153 26 (16.99%) 70 3 (4.29%) 978 33 (3.37%)

Seizure: MedDRA Codes Convulsion, Grand Mal Convulsion, Status Epilepticus, Convulsions Local, Febrile Convulsion

Reports with missing age and age 0 -5 months old were excluded

Vaccines type includes Inactivated only

a

IIV Includes all inactivated influenza vaccines (IIV3, IIV4, RIV3, ccIIV3)

b

Vaccination and Receive Date falls between 07/01 - 03/27 Per Season