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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Biomaterials. 2019 Apr 4;208:32–44. doi: 10.1016/j.biomaterials.2019.04.001

Figure 2 -. Bone regeneration in a critical-sized calvarial defect.

Figure 2 -

A) Representative microCT images of bone formation in the defect region at 10 weeks. MicroCT data were analyzed to specifically assess new bone in the 4 mm defect site across implant replicates, and to obtain quantitative measures of: B) total bone volume, C) mineral content, D) mineral density, and E) bone volume fraction (bone volume/tissue volume). F) Histology images of newly formed bone in the defect site using Movat’s pentachrome staining. (Collagen fibers= yellow; fibrin = bright red; nuclei = purple-black). Arrows indicate microvessels and * indicates primitive marrow cavities.