Table 4.

Number of genes assigned to functional groups up- and downregulated in ZW (genetic female) gonads

Functional gene groups	ZW (genetic females)
	NF53 vs. NF50		NF56 vs. NF53		NF62 vs. NF56
	Up	Down	Up	Down	Up	Down
Signaling factors	20	61	7	8	–	103
Calcium-binding proteins	6	–	3	–	–	–
Iron-binding proteins	4	–	–	–	–	–
Monooxygenases	4	–	–	–	–	11
Oxidoreductases	5	11	–	–	–	22
Sushi domain–containing proteins	2	–	–	–	–	–
Metalloproteinases	3	–	–	–	–	8
Intermediate filaments	3	–	–	–	–	–
EGF-like domain–containing proteins	3	–	–	–	–	–
ECM-receptor interaction pathway	3	–	–	–	–	–
Progesterone-mediated oocyte maturation pathway	4	–	–	–	11	–
Proteases	–	12	–	–	–	18
Hydrolases	–	27	–	–	–	33
Disulfide bond–containing proteins	–	–	5	–	–	45
Extracellular matrix components	–	–	–	5	–	–
Markers of epithelial differentiation	–	–	–	2	–	–
Meiosis regulation factors	–	–	–	–	8	–
RNA-binding proteins	–	–	–	–	15	–
Phosphoproteins	–	–	–	–	16	–
Proteins involved in development	–	–	–	–	22	–
Proteins involved in oogenesis	–	–	–	–	3	–
Cytoplasmic proteins	–	–	–	–	35	–
Cytoskeletal proteins	–	–	–	–	12	–
Proteins involved in differentiation	–	–	–	–	9	–
Nuclear proteins	–	–	–	–	45	–
Transcriptional repressors	–	–	–	–	8	–
DNA-binding proteins	–	–	–	–	3	–
Oocyte meiosis	–	–	–	–	10	–
p53 signaling	–	–	–	–	6	–
Basal transcription factors	–	–	–	–	4	–
Proteins involved in DNA Replication	–	–	–	–	4	–
Proteins involved in the formation of dorso-ventral axis	–	–	–	–	3	–
Secreted proteins	–	–	–	–	–	23
Transport proteins	–	–	–	–	–	36