Table 2.

Mean Within-Host Evolutionary Rates in Hepatitis C Virus Envelope Glycoprotein

		Within-Host Evolutionary Rate, 10–2 substitutions/site/year (95% Credible Interval)
		Individuals
Gene Region	Partition	p4	p37	p53	p61
E1	CP1 + 2	1.942 (1.467, 2.465)	0.193 (0.127, 0.257)	0.240 (0.132, 0.347)	0.211 (0.146, 0.278)
E2	CP1 + 2	1.791 (1.303, 2.248)	2.233 (1.602, 2.834)	0.363 (0.237, 0.504)	0.209 (0.159, 0.265)
HVR1	CP1 + 2	3.361 (1.805, 6.255)	4.841 (2.855, 6.727)	3.540 (1.113, 8.772)	1.475 (1.115, 1.921)
E1	CP3	0.476 (0.224, 0.747)	0.187 (0.119, 0.255)	0.202 (0.109, 0.295)	0.168 (0.129, 0.210)
E2	CP3	0.572 (0.425, 0.722)	0.443 (0.317, 0.584)	0.221 (0.135, 0.314)	0.257 (0.210, 0.313)
HVR1	CP3	0.726 (0.272, 1.123)	2.584 (0.927, 8.089)	0.896 (0.191, 1.865)	0.592 (0.271, 0.964)
Envelope	Total	2.390 (2.014, 2.824)	2.514 (2.030, 3.027)	0.749 (0.503, 1.037)	0.746 (0.650, 0.841)