Table 3.
Changes of microRNAs by acupuncture treatment in the other disease animal models.
| Disease model | Author | Year | Species | EA/MA | Acupoint | Acupuncture parameters | Tissue | Result |
|---|---|---|---|---|---|---|---|---|
| EA tolerance | Cui et al. | 2017 | Rat | EA | ST36, SP6 | 2 Hz/15 Hz, | Brain (hypothalamus) | ↑ miR-124, miR-107, |
| 3mA, 30 min | ↓ miR-148a, miR-370 | |||||||
| Postoperative ileus | Deng et al. | 2017 | Rat | MA | ST36, SP6, | 2-3 mm depth, | Colon | ↓ miR-19a |
| LR3 | 15 min | |||||||
| Chronic atrophic gastritis | Zhang et al. | 2016 | Rat | MA | ST36, CV20, | 3 mm depth, | Gastric tissue | ↑ miR-339, |
| BL20 | 15 min | ↓ miR-155, miR-21 | ||||||
| Chronic kidney disease | Hu et al. | 2015 | Mouse | EA | GB34, ST36 | 20 Hz, 1 mA, | Muscle | ↓ miR-1 |
| 15 min | ||||||||
| Hyperactivity of HPA axis | Zhu et al. | 2017 | Rat | EA | ST36, SP6 | 2 Hz/15 Hz, | Brain (hypothalamus) | ↑ miR-142, miR-376c |
| 2mA, 30 min | ||||||||
| Allergic contact dermatitis | Wang et al. | 2018 | Rat | EA | ST36 | 2 Hz, 1 mA, | Ear | ↓ miR-155 |
| 5 min, 20 min |
EA; electroacupuncture, MA; manual acupuncture, HPA; hypothalamic-pituitary-adrenal.