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. 2019 Apr 17;2019:1321973. doi: 10.1155/2019/1321973

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Copyright © 2019 Yang Song et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Resveratrol (Res) inhibits EMT generated stem cell-like properties of GBM cells. (a) Resveratrol (40μM) inhibited EMT-induced gliosphere formation. Representative images of gliosphere were photographed under Olympus microscope (×100 magnification). The numbers of gliosphere in different treatment groups were showed in histograms. (b) Western blotting showed that resveratrol inhibited EMT-induced upregulation of stemness-related proteins expression in a dose-dependent manner. Each independent experiment was repeated three times.