Table 2.

Studies included in our analysis detailing number of pediatric patients with individual data, level of evidence, and potential biases (< 5 patients, mixed adult and pediatric population, adolescents only, young children only, follow-up length)

Study	Number of patients	Study features
Cersosimo et al. [6]	7	Mixed population, variable long-term follow-up (1.2–7.7 years)
Ghosh et al. [13]	8	Adolescents only
Goto et al. [15]	2	< 5 patients, limited follow-up length (1 year)
Jin et al. [19]	1	Case report, young child
Keen et al. [22]	5	Mixed population, variable follow-up (0.16–3.50 years)
Krause et al. [23]	4	Mixed population (age and etiology), variable follow-up length (1–5.5 years)
Krause et al. [24]	1	Mixed population (only 1 patient met inclusion criteria)
Krause et al. [25]	6	Adolescents only
Kupsch et al. [26]	1	Case report, patient age not disclosed
Mehrkens et al. [33]	4	Mixed population
Miyagi et al. [36]	2	< 5 patients, young children only
Olaya et al. [37]	1	Limited long-term follow up (all less than 1 year)
Oterdoom et al. [38]	1	Case report, rare genetic mutation
Parr et al. [40]	4	< 5 patients, very young children < 2 years old
Petrossian et al. [41]	13	Mixed population, mixed etiology
Starr et al. [46]	1	Mixed population, sex unknown, mixed etiologies
Tronnier et al. [48]	1	< 5 patients, 1 pediatric patient
Vidailhet et al. [49]	5	Mixed population, limited to 1-year follow-up
Zorzi et al. [51]	9	Mixed population, variable follow-up (0.16–4.17 years)