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. 2019 Apr 30;12:3245–3254. doi: 10.2147/OTT.S202271

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© 2019 Shao et al.

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Pattern structure diagram of Annexin A1. The C-terminal core region of Annexin A1 is composed of four homologous repeats, while the N-terminal domain is composed of 44 amino acids with two α-helix. The N-terminal domain contains S100A11 binding sites and could be phosphorylated by TRMP7, PKC, and epidermal growth factor receptor kinase.