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Treatment with evobrutinib normalized clinical chemistry and hematology parameters. (A) Urea nitrogen, albumin, and cholesterol levels in NZB/W mice treated with evobrutinib, CellCept, or vehicle on day 56. Normal control (NC), young NZB/W mice not yet showing signs of proteinuria. (B) Numbers of RBCs, hemoglobin, and hematocrit in the same animals. One-way ANOVA with Dunnett posttest was performed for treated groups compared with vehicle. *p < 0.05, **p < 0.01, ***p < 0.001.
