Table 1.

Activity of XO and ALT in sickle cell disease

Measurement	Enzyme activity
	Control	SCD*
Human
Plasma XO (μU/ml)	0.89  ± 0.3 (15)	3.30  ± 0.9 (18)
Mouse
Plasma XO (mU/ml)	2.2  ± 0.26 (13)	5.6  ± 1.5 (15)
ALT (mU/ml)	24.2  ± 2.3 (10)	270.5  ± 24.5 (12)
Liver XO (mU/g tissue)	53.9  ± 7.8 (6)	18.6  ± 4.4 (6)
Aortic XO (mU/mg protein)	0.29  ± 0.01 (3)	0.46  ± 0.03 (4)

^*, P < 0.05 from control. n for each measurement is italicized in parentheses.