TABLE 3.

Key questions in the AHRQ sodium and potassium systematic review (19)¹

Nutrient	Key question
Sodium	1. Among adults and children of all age groups (including both sexes and pregnant and lactating women), what is the effect (benefits and harms) of interventions to reduce dietary sodium intake on blood pressure at the time of the study and in later life?
	2. Among adults and children, what is the association between dietary sodium intake and blood pressure?
	3. Among adults, what is the effect (benefits and harms) of interventions to reduce dietary sodium intake on CVD and kidney disease morbidity and mortality and on total mortality?
	4. Among adults, what is the association between dietary sodium intake and CVD, CHD, stroke, and kidney disease morbidity and mortality and between dietary sodium intake and total mortality?
Potassium	1. Among children and adults, what is the effect of interventions to increase potassium intake on blood pressure and kidney stone formation?
	2. Among children and adults, what is the association between potassium intake and blood pressure and kidney stone formation?
	3. Among adults, what is the effect of interventions aimed at increasing potassium intake on CVD and kidney disease morbidity and mortality, and total mortality?
	4. Among adults, what is the association between dietary potassium intake and CVD, CHD, stroke, and kidney disease morbidity and mortality, and between dietary potassium and total mortality?

¹AHRQ, Agency for Healthcare Research and Quality; CHD, coronary heart disease; CVD, cardiovascular disease.