TABLE 3.
Multivariate Analysis of Parameters Associated With PFS or OS
| Strata | Median | Test of equality over strata | Multiple comparisona | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| EOR | MGMT | code | Estimate | 95% CI | Chi-Sq | DF | P-value | P-value | |||
| PFS | |||||||||||
| Complete | Unmethylated | 1 | 275 | 248 | 386 | 10.6544 | 3 | .0137 | |||
| Complete | Methylated | 2 | 399 | 232 | 657 | 2 vs 3 | .0073 | ||||
| Incomplete | Unmethylated | 3 | 266 | 167 | 281 | ||||||
| Incomplete | Methylated | 4 | 256 | 161 | 323 | ||||||
| OS | |||||||||||
| Complete | Unmethylated | 1 | 541 | 470 | 604 | 21.291 | 3 | <.0001 | 1 vs 2 | .0109 | |
| Complete | Methylated | 2 | 842 | 543 | |||||||
| Incomplete | Unmethylated | 3 | 392 | 353 | 474 | 2 vs 3 | <.0001 | ||||
| Incomplete | Methylated | 4 | 519 | 360 | 837 | 2 vs 4 | .0324 | ||||
aTukey method was used for adjusting multiple comparisons.