TABLE 4.
Cox Regression Analysis of Overall Survival and Progression-Free Survival
| PFS | OS* | |||||
|---|---|---|---|---|---|---|
| Variables | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age (>60 vs ≤60) | 1.61 | 1.15-2.26 | .0052 | 2.12 | 1.46-3.1 | .0028 |
| Sex (male vs female) | – | |||||
| KPS(≤70 vs >70) | 1.43 | 1.01-2.01 | .0442 | – | ||
| EOR (incomplete vs complete) | 1.57 | 1.12-2.21 | .0092 | 1.75 | 1.21-2.53 | <.0001 |
| MGMT promoter (methylated vs non-methylated) | 1.53 | 1.08-2.16 | .0165 | 2.22 | 1.52-3.25 | <.0001 |
| Adjuvant therapy | 1.37 | 0.97-1.92 | .0715 | – | ||
–the variable was not selected in the stepwise Cox regression (using P = .1 as entry and stay).
*stratified (by sex) Cox-regression model was used since proportional hazard (PH) assumption for sex was violated.