Table 1.
The lowest drug concentration [ivermectin (IVM) or moxidectin (MOX)] at which a statistically significant increase (p=<0.05), judged by 2-way ANOVA, in cell attachment was observed compared to the no-drug control.
| Strain | Missouri | Georgia-2 | JYD-27 | Yazoo-2013 | Metairie-2014 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Drug | IVM | MOX | IVM | MOX | IVM | MOX | IVM | MOX | IVM | MOX |
| PMN | 3 nM | 3 nM | 1 nM | 3 nM | 3 nM | 10 nM | 100 nM | 3 nM | 1 μMa | 10 nM |
| PBMC | 3 nM | 1 nM | 1 nM | 1 nM | 10 nM | 1 nM | 100 nM | 10 nM | >1 μMa | 1 nM |
1 μM was the highest concentration of either drug tested.