Table 2.
CNA analyses in LGSOC.
| Author | Journal Publication year |
N° LGSOC |
CNA loss/gain | Candidate genes |
|---|---|---|---|---|
| Kuo et al. [33] | Cancer Res 2009 |
12 | Loss: Chr 1p36, Chr 9p21.3 | CHD5, MiR-34a CDKN2A/B |
| Birch et al. [13] | Plos One 2011 |
11 | Loss: chr 1p | - |
| Emmanuel et al. [9] | Clin Cancer Res 2014 |
13 | CNI identical between paired SBT and LGSOC samples Low CNI compared to HGSOC |
- |
| Hunter et al. [7] | Oncotarget 2015 |
13 | Loss: 1p, 9p, 22q Gain: 7, 8 |
CDKN2A/B |
| McIntyre et al. [28] | Histopathol 2017 |
26 | Only report on CNI Low CNI compared to HGSOC |
- |
| Total | 70 |
The most frequent CNAs are indicated. Chr, chromosome; CNI, copy number index.